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ACS Blood Test Guideline Is a Last Resort, Not a First Option — Here's What the Coverage Left Out

ACS Blood Test Guideline Is a Last Resort, Not a First Option — Here's What the Coverage Left Out
The American Cancer Society's new colorectal cancer screening guidelines made headlines for adding a blood test, but the fine print matters: the ACS explicitly calls that blood test a last resort for people who won't do anything else. More than 20 million eligible Americans are still unscreened, and colorectal cancer now hits 1 in 5 patients under 55. The nuance got buried.

The Headline Everyone Ran — And The Buried Caveat

Every outlet picked up the same hook: blood test, new guidelines, big deal. What most coverage glossed over is the part that actually matters.

The American Cancer Society released updated colorectal cancer screening guidelines this week in its flagship journal. Yes, they now include a blood-based screening test done in a doctor's office. But according to ABC News — citing the guidelines directly — that blood test is explicitly designated as a last resort for people who refuse or are unable to complete any other form of testing.

The ACS's own language: blood tests "are less likely to catch issues compared to other types of screening."

Most of the headlines missed this entirely.

What The Numbers Actually Say

Colorectal cancer is the top cancer killer of adults under 50 in the United States, according to ACS data.

1 in 5 new colorectal cancer cases now occur in people younger than 55. In the mid-1990s, that figure was roughly 1 in 10, according to ABC News reporting on the ACS statistics.

The NY Post reported a 50% relative increase in diagnoses among adults aged 45 to 49 just from 2021 to 2022. One year. Fifty percent.

Dr. Fola May, associate professor of medicine at UCLA's David Geffen School of Medicine, told ABC News: "This is a disease that historically, we saw in older individuals... And now we are starting to see an inching up of incidents in people who are less than age 50."

The Real Problem: One in Three Aren't Getting Tested At All

About one in three American adults eligible for colorectal cancer screening have NOT been tested, according to ACS research. More than 20 million eligible Americans remain unscreened, per the ACS figures cited by ABC News.

That's the actual crisis. Not which test you pick — the fact that tens of millions are picking none.

Dr. William Dahut, chief scientific officer at the ACS, told ABC News: "Individuals who decline or do not complete [testing] are probably a greater number than are actually appreciated. And I think a lot of our data on colorectal screening probably overstates the number of people actually up to date on their screening guidelines."

The official compliance numbers are likely inflated. The real screening gap is probably worse than reported.

The Guideline Update

The ACS is now recommending:

  • Adults at average risk start screening at age 45, continue through age 75 (for those with 10+ year life expectancy)
  • Colonoscopy remains the gold standard — done every 10 years
  • Stool-based tests done every 1, 3, or 5 years depending on the specific method
  • A blood-based test detecting tumor DNA in the blood is now included — but as a last resort, NOT a first-line option
  • A newly FDA-approved at-home stool test looking for blood and molecular markers is also added
  • Adults over 85 should no longer be screened at all, per the new guidelines
  • High-risk individuals may need to start before 45 or screen more frequently

Dr. Robert Smith, senior VP of early cancer detection science at the ACS and senior author of the report, stated that "colorectal cancer should be emphasized as a highly preventable disease as much as a treatable one." The five-year survival rate for early-stage detection exceeds 90% in the United States, according to the ACS.

What Mainstream Coverage Got Wrong

The NY Post and Yahoo Health ran nearly identical coverage — accurate but incomplete. Both led with the blood test angle without clearly flagging its last-resort status in the guidelines.

Fox News ran the story but the sourced content was largely a sidebar to unrelated health stories — not exactly a thorough treatment of a public health development affecting millions.

ABC News did the best job of the bunch, actually quoting Dr. Dahut's admission that compliance data is likely overstated. That's a significant concession from the ACS's own chief scientific officer, and it deserved far more attention than it got.

The story isn't "blood test now approved." Millions of Americans still aren't showing up for screening at all, and the new tools are secondary to that fundamental problem.

For Patients

If you're 45 or older and haven't been screened, stop waiting for a more convenient option to materialize. The colonoscopy you've been avoiding is still the best test available. The blood test isn't a free pass — the ACS itself says it catches less.

Colorectal cancer is highly preventable and highly survivable when caught early. It becomes neither of those things when you skip screening entirely.

The guidelines got updated. The human behavior hasn't. That's the problem no new test can fix.

Sources

center-right NY Post Doctors push new blood tests for colon cancer as cases surge in younger adults
right foxnews Doctors push new blood tests for colon cancer as cases surge in younger adults
unknown health.yahoo Doctors push new blood tests for colon cancer as cases surge in younger adults
unknown abcnews New guidelines could help millions more Americans get colon cancer testing - ABC News